Synthesis of new 1,2,3-triazole derivatives possessing 4H-pyran-4-one moiety by 1,3-dipolar cycloaddition reaction of azidomethyl phenylpyrone with various alkynes

Title: Synthesis of new 1,2,3-triazole derivatives possessing 4H-pyran-4-one moiety by 1,3-dipolar cycloaddition reaction of azidomethyl phenylpyrone with various alkynes

Author(s): Eftekhari-Sis B.,Faramarzi M.,Hossienzadeh R.,Saraei M.

منبع: Journal of Heterocyclic Chemistry : Volume 51, Issue 5, 2014 , Pages 1500-1503

نمایه شده در: Crossref Scopus WOS

شناسه دیجیتال: DOI:10.1002/jhet.1743

شناسه اختصاصی:

993-474-394-549

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لینک دانلود: [درخواست از نویسنده برای دریافت منبع] [دانلود از طریق گوگل اسکالر]

لینک ناشر: http://dx.doi.org/10.1002/jhet.1743

A series of new 1,2,3-triazole derivatives were synthesized by 1,3-dipolar cycloaddition reaction of 2-(4-azidomethylphenyl)-6-phenyl-4H-pyran-4-one with different alkynes in 40-71% yields. In the case of terminal alkynes, the reaction was proceeded in the presence of Cu(I) catalyst. The structure of the synthesized compounds were confirmed by FTIR, 1H-NMR, and 13C-NMR spectroscopy and elemental analysis. Â© 2014 HeteroCorporation.

Keywords
alkyne Article ethyl 1 [4 (4 oxo 6 phenyl 4h pyran 2 yl)benzyl] 1,2,3 triazole 4 carboxylic acid proton nuclear magnetic resonance cycloaddition 1,2,3 triazole derivative 2 [4 [(4 hydroxyethyl 1,2,3 triazol 1 yl)methyl]phenyl] 6 phenyl 4h pyran 4 one carbon nuclear magnetic resonance infrared spectroscopy drug synthesis methyl 1 [4 (4 oxo 6 phenyl 4h pyran 2 yl)benzyl] 1,2,3 triazole 4 carboxylic acid catalyst dimethyl 1 [4 (4 oxo 6 phenyl 4h pyran 2 yl)benzyl] 1,2,3 triazole 4,5 dicarboxylic acid unclassified drug azide 2 phenyl 6 [[4 (4 phenyl 1,2,3 triazol 1 yl)methyl]phenyl] 4h pyran 4 one diethyl 1 [4 (4 oxo 6 phenyl 4h pyran 2 yl)benzyl] 1,2,3 triazole 4,5 dicarboxylic acid 4 pyrone derivative drug structure copper 2 [4 [(4 hydroxymethyl 1,2,3 triazol 1 yl)methyl]phenyl] 6 phenyl 4h pyran 4 one 2 (4 azidomethylphenyl) 6 phenyl 4h pyran 4 one derivative

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